{"symbol":"SEMA5B","synonyms":["SEMAG"],"name":"sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B","description":"This gene encodes a member of the semaphorin protein family which regulates axon growth during development of the nervous system. The encoded protein has a characteristic Sema domain near the N-terminus, through which semaphorins bind to plexin, and five thrombospondin type 1 repeats in the C-terminal region of the protein. The protein product may be cleaved and exist as a secreted molecule (PMID: 19463192). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]","ncbiEntrezGeneId":54437,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/54437","proteins":[{"symbol":"SEM5B_HUMAN","href":"/api/1.0/protein/SEM5B_HUMAN"}],"hgncRootFamilies":[{"name":"Semaphorins (SEMA)","href":"/api/1.0/gene_family/Semaphorins+%28SEMA%29"}]}