{"symbol":"SEPT1","synonyms":["DIFF6","PNUTL3"],"name":"septin 1","description":"This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer\u0027s disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]","ncbiEntrezGeneId":1731,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1731","proteins":[{"symbol":"SEPT1_HUMAN","href":"/api/1.0/protein/SEPT1_HUMAN"}],"hgncRootFamilies":[{"name":"Septins (SEPT)","href":"/api/1.0/gene_family/Septins+%28SEPT%29"}]}