{"symbol":"SERPINB1","synonyms":["LEI","ELANH2","HEL57","EI","HEL-S-27","MNEI","PI-2","M/NEI","PI2"],"name":"serpin peptidase inhibitor, clade B (ovalbumin), member 1","description":"The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]","ncbiEntrezGeneId":1992,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1992","proteins":[{"symbol":"ILEU_HUMAN","href":"/api/1.0/protein/ILEU_HUMAN"}],"hgncRootFamilies":[{"name":"Serpin peptidase inhibitors (SERPIN)","href":"/api/1.0/gene_family/Serpin+peptidase+inhibitors+%28SERPIN%29"}]}