{"symbol":"SERPINB8","synonyms":["CAP2","PI-8","PSS5","PI8"],"name":"serpin peptidase inhibitor, clade B (ovalbumin), member 8","description":"The protein encoded by this gene is a member of the ov-serpin family of serine protease inhibitors. The encoded protein is produced by platelets and can bind to and inhibit the function of furin, a serine protease involved in platelet functions. In addition, this protein has been found to enhance the mechanical stability of cell-cell adhesion in the skin, and defects in this gene have been associated with an autosomal-recessive form of exfoliative ichthyosis. [provided by RefSeq, Jan 2017]","ncbiEntrezGeneId":5271,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5271","proteins":[{"symbol":"SPB8_HUMAN","href":"/api/1.0/protein/SPB8_HUMAN"}],"hgncRootFamilies":[{"name":"Serpin peptidase inhibitors (SERPIN)","href":"/api/1.0/gene_family/Serpin+peptidase+inhibitors+%28SERPIN%29"}]}