{"symbol":"SERPINE2","synonyms":["PI7","GDN","PI-7","PN1","PN-1","GDNPF","PNI"],"name":"serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2","description":"This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]","ncbiEntrezGeneId":5270,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5270","proteins":[{"symbol":"GDN_HUMAN","href":"/api/1.0/protein/GDN_HUMAN"}],"hgncRootFamilies":[{"name":"Serpin peptidase inhibitors (SERPIN)","href":"/api/1.0/gene_family/Serpin+peptidase+inhibitors+%28SERPIN%29"}]}