{"symbol":"SETD8","synonyms":["KMT5A","SET07","PR-SET7","SET8"],"name":"SET domain containing (lysine methyltransferase) 8","description":"The protein encoded by this gene is a protein-lysine N-methyltransferase that can monomethylate Lys-20 of histone H4 to effect transcriptional repression of some genes. The encoded protein is required for cell proliferation and plays a role in chromatin condensation. [provided by RefSeq, May 2016]","ncbiEntrezGeneId":387893,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/387893","proteins":[{"symbol":"SETD8_HUMAN","href":"/api/1.0/protein/SETD8_HUMAN"}],"hgncRootFamilies":[{"name":"Chromatin-modifying enzymes","href":"/api/1.0/gene_family/Chromatin-modifying+enzymes"}]}