{"symbol":"SETX","synonyms":["ALS4","BA479K20.2","AOA2"],"name":"senataxin","description":"This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4). [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":23064,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23064","proteins":[{"symbol":"SETX_HUMAN","href":"/api/1.0/protein/SETX_HUMAN"}],"hgncRootFamilies":[]}