{"symbol":"SFRP2","synonyms":["FRP-2","SDF-5","SARP1"],"name":"secreted frizzled-related protein 2","description":"This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":6423,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6423","proteins":[{"symbol":"SFRP2_HUMAN","href":"/api/1.0/protein/SFRP2_HUMAN"}],"hgncRootFamilies":[{"name":"Secreted frizzled-related proteins (SFRP)","href":"/api/1.0/gene_family/Secreted+frizzled-related+proteins+%28SFRP%29"}]}