{"symbol":"SH3RF1","synonyms":["POSH","SH3MD2","RNF142"],"name":"SH3 domain containing ring finger 1","description":"This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":57630,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/57630","proteins":[{"symbol":"SH3R1_HUMAN","href":"/api/1.0/protein/SH3R1_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}