{"symbol":"SI","synonyms":[],"name":"sucrase-isomaltase (alpha-glucosidase)","description":"This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.[provided by RefSeq, Apr 2010]","ncbiEntrezGeneId":6476,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6476","proteins":[{"symbol":"SUIS_HUMAN","href":"/api/1.0/protein/SUIS_HUMAN"}],"hgncRootFamilies":[]}