{"symbol":"SIGLEC1","synonyms":["CD169","DJ1009E24.1","SIGLEC-1","SN"],"name":"sialic acid binding Ig-like lectin 1, sialoadhesin","description":"This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. The protein plays an important role in multiple human diseases and bacterial and viral infections has been shown to enhance SARS-CoV-2 infection. [provided by RefSeq, Dec 2021]","ncbiEntrezGeneId":6614,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6614","proteins":[{"symbol":"SN_HUMAN","href":"/api/1.0/protein/SN_HUMAN"}],"hgncRootFamilies":[{"name":"Sialic acid binding Ig-like lectins (SIGLECs)","href":"/api/1.0/gene_family/Sialic+acid+binding+Ig-like+lectins+%28SIGLECs%29"},{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"},{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"}]}