{"symbol":"SLC22A1","synonyms":["OCT1_CDS","HOCT1"],"name":"solute carrier family 22 (organic cation transporter), member 1","description":"Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":6580,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6580","proteins":[{"symbol":"S22A1_HUMAN","href":"/api/1.0/protein/S22A1_HUMAN"}],"hgncRootFamilies":[{"name":"Solute carriers (SLC)","href":"/api/1.0/gene_family/Solute+carriers+%28SLC%29"}]}