{"symbol":"SLC22A2","synonyms":["OCT2"],"name":"solute carrier family 22 (organic cation transporter), member 2","description":"Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":6582,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6582","proteins":[{"symbol":"S22A2_HUMAN","href":"/api/1.0/protein/S22A2_HUMAN"}],"hgncRootFamilies":[{"name":"Solute carriers (SLC)","href":"/api/1.0/gene_family/Solute+carriers+%28SLC%29"}]}