{"symbol":"SLC5A12","synonyms":["SMCT2"],"name":"solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12","description":"Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]).[supplied by OMIM, Dec 2008]","ncbiEntrezGeneId":159963,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/159963","proteins":[{"symbol":"SC5AC_HUMAN","href":"/api/1.0/protein/SC5AC_HUMAN"}],"hgncRootFamilies":[{"name":"Solute carriers (SLC)","href":"/api/1.0/gene_family/Solute+carriers+%28SLC%29"}]}