{"symbol":"SLC8A2","synonyms":["NCX2"],"name":"solute carrier family 8 (sodium/calcium exchanger), member 2","description":"Predicted to enable calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration and calcium:sodium antiporter activity. Predicted to be involved in several processes, including learning or memory; monoatomic cation transmembrane transport; and regulation of short-term neuronal synaptic plasticity. Predicted to act upstream of or within several processes, including modulation of chemical synaptic transmission; regulation of action potential firing pattern; and response to ischemia. Located in presynapse. Biomarker of Alzheimer\u0027s disease. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":6543,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6543","proteins":[{"symbol":"NAC2_HUMAN","href":"/api/1.0/protein/NAC2_HUMAN"}],"hgncRootFamilies":[{"name":"Solute carriers (SLC)","href":"/api/1.0/gene_family/Solute+carriers+%28SLC%29"}]}