{"symbol":"SLC9A3R2","synonyms":["NHERF-2","E3KARP","TKA-1","NHERF2","NHE3RF2","SIP-1","OCTS2"],"name":"solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2","description":"This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]","ncbiEntrezGeneId":9351,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9351","proteins":[{"symbol":"NHRF2_HUMAN","href":"/api/1.0/protein/NHRF2_HUMAN"}],"hgncRootFamilies":[]}