{"symbol":"SLCO1C1","synonyms":["OATPF","SLC21A14","OATP1C1","OATPRP5","OATP-F","OATP14"],"name":"solute carrier organic anion transporter family, member 1C1","description":"This gene encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]","ncbiEntrezGeneId":53919,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/53919","proteins":[{"symbol":"SO1C1_HUMAN","href":"/api/1.0/protein/SO1C1_HUMAN"}],"hgncRootFamilies":[{"name":"Solute carriers (SLC)","href":"/api/1.0/gene_family/Solute+carriers+%28SLC%29"}]}