{"symbol":"SMC5","synonyms":["SMC5L1"],"name":"structural maintenance of chromosomes 5","description":"Enables DNA secondary structure binding activity. Involved in several processes, including DNA recombination; negative regulation by host of viral genome replication; and positive regulation of cell cycle process. Located in cell junction; chromosome; and nuclear body. Part of Smc5-Smc6 complex. Is active in nucleus. Implicated in mosaic variegated aneuploidy syndrome. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":23137,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23137","proteins":[{"symbol":"SMC5_HUMAN","href":"/api/1.0/protein/SMC5_HUMAN"}],"hgncRootFamilies":[{"name":"Structural maintenance of chromosomes proteins (SMC)","href":"/api/1.0/gene_family/Structural+maintenance+of+chromosomes+proteins+%28SMC%29"}]}