{"symbol":"SMC6","synonyms":["SMC-6","HSMC6","SMC6L1"],"name":"structural maintenance of chromosomes 6","description":"Enables DNA secondary structure binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including cellular senescence; negative regulation by host of viral genome replication; and telomere maintenance via recombination. Located in chromosome and nuclear body. Part of Smc5-Smc6 complex. Is active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":79677,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79677","proteins":[{"symbol":"SMC6_HUMAN","href":"/api/1.0/protein/SMC6_HUMAN"}],"hgncRootFamilies":[{"name":"Structural maintenance of chromosomes proteins (SMC)","href":"/api/1.0/gene_family/Structural+maintenance+of+chromosomes+proteins+%28SMC%29"}]}