{"symbol":"SNAP91","synonyms":["AP180"],"name":"synaptosomal-associated protein, 91kDa","description":"Predicted to enable several functions, including clathrin adaptor activity; clathrin heavy chain binding activity; and phosphatidylinositol binding activity. Acts upstream of or within regulation of clathrin-dependent endocytosis. Predicted to be located in cytosol; postsynaptic density; and synaptic membrane. Predicted to be active in several cellular components, including Schaffer collateral - CA1 synapse; cytoplasmic vesicle; and parallel fiber to Purkinje cell synapse. Predicted to be extrinsic component of presynaptic endocytic zone membrane. Biomarker of Alzheimer\u0027s disease. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":9892,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9892","proteins":[{"symbol":"AP180_HUMAN","href":"/api/1.0/protein/AP180_HUMAN"}],"hgncRootFamilies":[]}