{"symbol":"SNX19","synonyms":["CHET8"],"name":"sorting nexin 19","description":"Islet antigen-2 (IA-2) is an autoantigen in type 1 diabetes and plays a role in insulin secretion. IA-2 is found in dense-core secretory vesicles and interacts with the product of this gene, a sorting nexin. In mouse pancreatic beta-cells, the encoded protein influenced insulin secretion by stabilizing the number of dense-core secretory vesicles. [provided by RefSeq, Dec 2016]","ncbiEntrezGeneId":399979,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/399979","proteins":[{"symbol":"SNX19_HUMAN","href":"/api/1.0/protein/SNX19_HUMAN"}],"hgncRootFamilies":[{"name":"Sorting nexins (SNX)","href":"/api/1.0/gene_family/Sorting+nexins+%28SNX%29"}]}