{"symbol":"SNX5","synonyms":[],"name":"sorting nexin 5","description":"This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis. This gene may play a role in the tumorigenesis of papillary thyroid carcinoma. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]","ncbiEntrezGeneId":27131,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/27131","proteins":[{"symbol":"SNX5_HUMAN","href":"/api/1.0/protein/SNX5_HUMAN"}],"hgncRootFamilies":[{"name":"Sorting nexins (SNX)","href":"/api/1.0/gene_family/Sorting+nexins+%28SNX%29"}]}