{"symbol":"SOAT1","synonyms":["ACAT-1","STAT","ACAT1","ACACT"],"name":"sterol O-acyltransferase 1","description":"The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]","ncbiEntrezGeneId":6646,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6646","proteins":[{"symbol":"SOAT1_HUMAN","href":"/api/1.0/protein/SOAT1_HUMAN"}],"hgncRootFamilies":[]}