{"symbol":"SOX3","synonyms":["PHPX","MRGH","GHDX","SOXB"],"name":"SRY (sex determining region Y)-box 3","description":"This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked cognitive disability with growth hormone deficiency. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":6658,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6658","proteins":[{"symbol":"SOX3_HUMAN","href":"/api/1.0/protein/SOX3_HUMAN"}],"hgncRootFamilies":[{"name":"SRY (sex determining region Y)-boxes (SOX)","href":"/api/1.0/gene_family/SRY+%28sex+determining+region+Y%29-boxes+%28SOX%29"}]}