{"symbol":"SP110","synonyms":["IPR1","IFI41","IFI75","VODI"],"name":"SP110 nuclear body protein","description":"The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":3431,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3431","proteins":[{"symbol":"SP110_HUMAN","href":"/api/1.0/protein/SP110_HUMAN"}],"hgncRootFamilies":[{"name":"Minor histocompatibility antigens","href":"/api/1.0/gene_family/Minor+histocompatibility+antigens"}]}