{"symbol":"SPINK1","synonyms":["TATI","PCTT","PSTI","TCP","SPINK3"],"name":"serine peptidase inhibitor, Kazal type 1","description":"The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008]","ncbiEntrezGeneId":6690,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6690","proteins":[{"symbol":"ISK1_HUMAN","href":"/api/1.0/protein/ISK1_HUMAN"}],"hgncRootFamilies":[{"name":"Serine peptidase inhibitors, Kazal type (SPINK)","href":"/api/1.0/gene_family/Serine+peptidase+inhibitors%2C+Kazal+type+%28SPINK%29"}]}