{"symbol":"SPPL2A","synonyms":["PSL2"],"name":"signal peptide peptidase like 2A","description":"This gene encodes a member of the GXGD family of aspartic proteases, which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions, as well as a member of the signal peptide peptidase-like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15. [provided by RefSeq, Feb 2012]","ncbiEntrezGeneId":84888,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/84888","proteins":[{"symbol":"SPP2A_HUMAN","href":"/api/1.0/protein/SPP2A_HUMAN"}],"hgncRootFamilies":[]}