{"symbol":"SPPL3","synonyms":["PRO4332","PSL4","MDHV1887","PSH1"],"name":"signal peptide peptidase like 3","description":"Enables aspartic endopeptidase activity, intramembrane cleaving and protein homodimerization activity. Involved in T cell receptor signaling pathway; membrane protein proteolysis; and positive regulation of calcineurin-NFAT signaling cascade. Located in Golgi-associated vesicle membrane; endoplasmic reticulum; and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":121665,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/121665","proteins":[{"symbol":"SPPL3_HUMAN","href":"/api/1.0/protein/SPPL3_HUMAN"}],"hgncRootFamilies":[]}