{"symbol":"SRA1","synonyms":["PP7684","SRAP","STRAA1"],"name":"steroid receptor RNA activator 1","description":"Both long non-coding and protein-coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non-coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non-NR activities, including metabolism, adipogenesis and chromatin organization. The long non-coding RNA transcripts interact with a variety of proteins, including the protein encoded by this gene. The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA. [provided by RefSeq, Mar 2012]","ncbiEntrezGeneId":10011,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10011","proteins":[{"symbol":"SRA1_HUMAN","href":"/api/1.0/protein/SRA1_HUMAN"}],"hgncRootFamilies":[]}