{"symbol":"SRCAP","synonyms":["EAF1","FLHS","DOMO1","SWR1"],"name":"Snf2-related CREBBP activator protein","description":"This gene encodes the core catalytic component of the multiprotein chromatin-remodeling SRCAP complex. The encoded protein is an ATPase that is necessary for the incorporation of the histone variant H2A.Z into nucleosomes. It can function as a transcriptional activator in Notch-mediated, CREB-mediated and steroid receptor-mediated transcription. Mutations in this gene cause Floating-Harbor syndrome, a rare disorder characterized by short stature, language deficits and dysmorphic facial features. [provided by RefSeq, Feb 2012]","ncbiEntrezGeneId":10847,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10847","proteins":[{"symbol":"SRCAP_HUMAN","href":"/api/1.0/protein/SRCAP_HUMAN"}],"hgncRootFamilies":[]}