{"symbol":"SRD5A3","synonyms":["CDG1P","CDG1Q","SRD5A2L","KRIZI","SRD5A2L1"],"name":"steroid 5 alpha-reductase 3","description":"The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq. [provided by RefSeq, Mar 2011]","ncbiEntrezGeneId":79644,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79644","proteins":[{"symbol":"PORED_HUMAN","href":"/api/1.0/protein/PORED_HUMAN"}],"hgncRootFamilies":[]}