{"symbol":"SREBF2","synonyms":["BHLHD2","SREBP-2","SREBP2"],"name":"sterol regulatory element binding transcription factor 2","description":"This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]","ncbiEntrezGeneId":6721,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6721","proteins":[{"symbol":"SRBP2_HUMAN","href":"/api/1.0/protein/SRBP2_HUMAN"}],"hgncRootFamilies":[{"name":"Basic helix-loop-helix proteins (BHLH)","href":"/api/1.0/gene_family/Basic+helix-loop-helix+proteins+%28BHLH%29"}]}