{"symbol":"SRGAP2","synonyms":["ARHGAP34","SRGAP3","SRGAP2A","FNBP2"],"name":"SLIT-ROBO Rho GTPase activating protein 2","description":"This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014]","ncbiEntrezGeneId":23380,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23380","proteins":[{"symbol":"SRGP2_HUMAN","href":"/api/1.0/protein/SRGP2_HUMAN"}],"hgncRootFamilies":[{"name":"Rho GTPase activating proteins (ARHGAP)","href":"/api/1.0/gene_family/Rho+GTPase+activating+proteins+%28ARHGAP%29"}]}