{"symbol":"SRSF10","synonyms":["SRP38","TASR","PPP1R149","TASR1","NSSR","SRRP40","FUSIP1","FUSIP2","SFRS13A","SFRS13","TASR2"],"name":"serine/arginine-rich splicing factor 10","description":"This gene product is a member of the serine-arginine (SR) family of proteins, which are involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein interacts with the oncoprotein TLS, and abrogates the influence of TLS on adenovirus E1A pre-mRNA splicing. This gene has pseudogenes on chromosomes 4, 9, 14, 18, and 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]","ncbiEntrezGeneId":10772,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10772","proteins":[{"symbol":"SRS10_HUMAN","href":"/api/1.0/protein/SRS10_HUMAN"}],"hgncRootFamilies":[{"name":"RNA binding motif containing (RBM)","href":"/api/1.0/gene_family/RNA+binding+motif+containing+%28RBM%29"},{"name":"Serine/arginine-rich splicing factors (SRSF)","href":"/api/1.0/gene_family/Serine%24slash%24arginine-rich+splicing+factors+%28SRSF%29"},{"name":"Protein phosphatase 1 regulatory subunits (PPP1R)","href":"/api/1.0/gene_family/Protein+phosphatase+1+regulatory+subunits+%28PPP1R%29"}]}