{"symbol":"SRSF4","synonyms":["SFRS4","SRP75"],"name":"serine/arginine-rich splicing factor 4","description":"Enables RNA binding activity. Involved in negative regulation of mRNA splicing, via spliceosome. Located in nuclear speck. Biomarker of Down syndrome; acute myeloid leukemia; clear cell renal cell carcinoma; and colon adenocarcinoma. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":6429,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6429","proteins":[{"symbol":"SRSF4_HUMAN","href":"/api/1.0/protein/SRSF4_HUMAN"}],"hgncRootFamilies":[{"name":"RNA binding motif containing (RBM)","href":"/api/1.0/gene_family/RNA+binding+motif+containing+%28RBM%29"},{"name":"Serine/arginine-rich splicing factors (SRSF)","href":"/api/1.0/gene_family/Serine%24slash%24arginine-rich+splicing+factors+%28SRSF%29"}]}