{"symbol":"ST8SIA1","synonyms":["SIAT8A","ST8SIAI","SIAT8","GD3S","SIAT8-A"],"name":"ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1","description":"Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015]","ncbiEntrezGeneId":6489,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6489","proteins":[{"symbol":"SIA8A_HUMAN","href":"/api/1.0/protein/SIA8A_HUMAN"}],"hgncRootFamilies":[{"name":"Glycosyltransferases","href":"/api/1.0/gene_family/Glycosyltransferases"}]}