{"symbol":"STARD13","synonyms":["GT650","ARHGAP37","DLC2","LINC00464"],"name":"StAR-related lipid transfer (START) domain containing 13","description":"This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]","ncbiEntrezGeneId":90627,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/90627","proteins":[{"symbol":"STA13_HUMAN","href":"/api/1.0/protein/STA13_HUMAN"}],"hgncRootFamilies":[{"name":"StAR-related lipid transfer (START) domain containing (STARD)","href":"/api/1.0/gene_family/StAR-related+lipid+transfer+%28START%29+domain+containing+%28STARD%29"},{"name":"Rho GTPase activating proteins (ARHGAP)","href":"/api/1.0/gene_family/Rho+GTPase+activating+proteins+%28ARHGAP%29"}]}