{"symbol":"STK10","synonyms":["PRO2729","LOK"],"name":"serine/threonine kinase 10","description":"This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":6793,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6793","proteins":[{"symbol":"STK10_HUMAN","href":"/api/1.0/protein/STK10_HUMAN"}],"hgncRootFamilies":[]}