{"symbol":"SUFU","synonyms":["PRO1280","SUFUH","SUFUXL","JBTS32"],"name":"suppressor of fused homolog (Drosophila)","description":"The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]","ncbiEntrezGeneId":51684,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/51684","proteins":[{"symbol":"SUFU_HUMAN","href":"/api/1.0/protein/SUFU_HUMAN"}],"hgncRootFamilies":[]}