{"symbol":"SUMO2","synonyms":["HSMT3","SMT3H2","SUMO3"],"name":"small ubiquitin-like modifier 2","description":"This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":6613,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6613","proteins":[{"symbol":"SUMO2_HUMAN","href":"/api/1.0/protein/SUMO2_HUMAN"}],"hgncRootFamilies":[]}