{"symbol":"SYVN1","synonyms":["HRD1","DER3"],"name":"synovial apoptosis inhibitor 1, synoviolin","description":"This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Sequence analysis identified two transcript variants that encode different isoforms. [provided by RefSeq, May 2011]","ncbiEntrezGeneId":84447,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/84447","proteins":[{"symbol":"SYVN1_HUMAN","href":"/api/1.0/protein/SYVN1_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}