{"symbol":"TAF1B","synonyms":["RAF1B","RAFI63","TAFI63","MGC:9349"],"name":"TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa","description":"Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]","ncbiEntrezGeneId":9014,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9014","proteins":[{"symbol":"TAF1B_HUMAN","href":"/api/1.0/protein/TAF1B_HUMAN"}],"hgncRootFamilies":[]}