{"symbol":"TAF8","synonyms":["43","TAF(II)43","TAFII-43","TAFII43","TBN"],"name":"TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa","description":"This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":129685,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/129685","proteins":[{"symbol":"TAF8_HUMAN","href":"/api/1.0/protein/TAF8_HUMAN"}],"hgncRootFamilies":[]}