{"symbol":"TALDO1","synonyms":["TALH","TALDOR","TAL-H","TAL"],"name":"transaldolase 1","description":"Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":6888,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6888","proteins":[{"symbol":"TALDO_HUMAN","href":"/api/1.0/protein/TALDO_HUMAN"}],"hgncRootFamilies":[]}