{"symbol":"TAX1BP1","synonyms":["CALCOCO3","TXBP151","T6BP"],"name":"Tax1 (human T-cell leukemia virus type I) binding protein 1","description":"This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]","ncbiEntrezGeneId":8887,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8887","proteins":[{"symbol":"TAXB1_HUMAN","href":"/api/1.0/protein/TAXB1_HUMAN"}],"hgncRootFamilies":[]}