{"symbol":"TBX3","synonyms":["TBX3-ISO","XHL","UMS"],"name":"T-box 3","description":"This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":6926,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6926","proteins":[{"symbol":"TBX3_HUMAN","href":"/api/1.0/protein/TBX3_HUMAN"}],"hgncRootFamilies":[{"name":"T-boxes (TBX)","href":"/api/1.0/gene_family/T-boxes+%28TBX%29"}]}