{"symbol":"TCTN1","synonyms":["JBTS13","TECT1"],"name":"tectonic family member 1","description":"This gene encodes a member of a family of secreted and transmembrane proteins. The orthologous gene in mouse functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. This protein is a component of the tectonic-like complex, which forms a barrier between the ciliary axoneme and the basal body. A mutation in this gene was found in a family with Joubert syndrome-13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]","ncbiEntrezGeneId":79600,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79600","proteins":[{"symbol":"TECT1_HUMAN","href":"/api/1.0/protein/TECT1_HUMAN"}],"hgncRootFamilies":[{"name":"Tectonic proteins (TCTN)","href":"/api/1.0/gene_family/Tectonic+proteins+%28TCTN%29"}]}