{"symbol":"TDP2","synonyms":["DJ30M3.3","HTDP2","TTRAP","AD022","EAPII"],"name":"tyrosyl-DNA phosphodiesterase 2","description":"This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":51567,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/51567","proteins":[{"symbol":"TYDP2_HUMAN","href":"/api/1.0/protein/TYDP2_HUMAN"}],"hgncRootFamilies":[]}