{"symbol":"TGFBI","synonyms":["LCD1","CDGG1","BIGH3","CDB1","EBMD","CDG2","CSD2","CSD3","CSD1"],"name":"transforming growth factor, beta-induced, 68kDa","description":"This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":7045,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7045","proteins":[{"symbol":"BGH3_HUMAN","href":"/api/1.0/protein/BGH3_HUMAN"}],"hgncRootFamilies":[]}