{"symbol":"TGIF2","synonyms":[],"name":"TGFB-induced factor homeobox 2","description":"The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene. [provided by RefSeq, Dec 2010]","ncbiEntrezGeneId":60436,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/60436","proteins":[{"symbol":"TGIF2_HUMAN","href":"/api/1.0/protein/TGIF2_HUMAN"}],"hgncRootFamilies":[{"name":"Homeoboxes","href":"/api/1.0/gene_family/Homeoboxes"}]}